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protonix 80 mg bid After reviewing evidence from a large, randomized, controlled trial, the task force determined that a reasonable balance of benefits and harms can be reached by screening people who are 55 to 80 years old and have a 30 “pack year” or greater history of smoking, who are either current smokers or have quit in the past 15 years. A “pack year” means that someone has smoked an average of one pack of cigarettes per day for a year. You reach 30 pack years of smoking history by smoking a pack a day for 30 years or two packs a day for 15 years.